Toxicity assessment and chemical properties of dolomite for use in dentistry

Autores

  • Gisele Fernandes Dias Universidade Estadual de Ponta Grossa - UEPG
  • Fabiana Bucholdz Teixeira Alves Universidade Estadual de Ponta Grossa - UEPG
  • André Vitor Chaves de Andrade Universidade Estadual de Ponta Grossa - UEPG
  • Aline Mara Ferreira Universidade Estadual de Ponta Grossa - UEPG
  • Fábio André dos Santos Universidade Estadual de Ponta Grossa - UEPG

DOI:

https://doi.org/10.26843/ro_unicidv3012018p33-46

Palavras-chave:

Chemical properties, Toxicity, PH, Ions, Calcification, Minerals, Inorganic particles

Resumo

The dolomite (DMT) can affect the metabolism of calcium and hydroxyl ions mineralization. To evaluate the toxicity, chemical properties and release of calcium and magnesium ions about 4 samples of DMT: Bioficina® - DMT I, Flora Pinhais® - DMT II, Dolomitex® - DMT III and Gran-White - DMT IV and hydroxide calcium PA (Biodinâmica® - HCA). Through bioassay Artemia Salina, hydrogen potential (pH), atomic absorption, X-ray diffraction (XRD) and X-ray fluorescence (XRF) of 4 samples of DMT was verified that the samples are suitable for potential use in dental materials. XRD and XRF techniques allowed to characterize the spatial conformation of the unit cell of dolomite, crystalline phases, mass percentage of chemical elements present in the samples. The presence of crystalline phases in addition to DMT has been identified as quartz and calcite. Impurities were detected in small amounts (Fe, K, Sr, Tm, S, Cu) and HCa to expectations about 100% portlandite. The pH was measured at concentrations of 1000 μg/mL;750 μg/mL;500 μg/mL;250 μg/ml and 100 ug/ml of the diluted crude extract of the sample at initial (0) and the periods of 24 and 168 hours wich were characterized in alkalinity pattern. In the interpretation of XRD and XRF tests have been detected the presence of silica, calcite and impurities besides the pure DMT in trace amounts in 2 samples while HCa to expectations of approximately 100% portlandite. To determine the toxicity was used the alternative method of lethal concentration 50 (CL50) with the bioassay model Artemia Salina. It resulted in low level of toxicity of DMTs with insignificant difference between times 24 and 48 hours. There was a release of 100ppm calcium and 32 ppm magnesium ions. None of the samples showed a significant percentage of other constituents considered harmful to health. It could be concluded that DMT is non-toxic, alkaline pH, considerable release of calcium ions, with crystalline phase that is characterized as a potential dental use.

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Referências

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Publicado

2018-10-02

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Artigos originais / Original Articles